Transport Reversal during Heteroexchange: A Kinetic Study

Transport Reversal during Heteroexchange: A Kinetic Study

It is known that secondary transporters, which utilize transmembrane ionic gradients to drive their substrates up a concentration gradient, can reverse the uptake and instead release their substrates. Unfortunately, the Michaelis-Menten kinetic scheme, which is popular in transporter studies, does not include transporter reversal, and it completely neglects the possibility of equilibrium betwee...

Glutamate transport - relative rates of net uptake and heteroexchange

A kinetic study of sulphate transport in rat liver mitochondria.

The kinetics of sulphate uptake catalysed by the dicarboxylate carrier were measured. The Km value for sulphate is about 0.3 mM. A completely competitive relation exists between the influxes of sulphate and malonate, whereas the relation between sulphate and phosphate is of the mixed type. The inhibition of sulphate influx by mersalyl and bathophenanthroline is similar to that of malonate influ...

A Kinetic Investigation of a Carrier-Mediated Transport through a Bulk Liquid Membrane

The kinetics of the potassium thiocyanate transport mediated by dicyclohexyl-18-crown-6 (L) through a bulk liquid membrane is studied experimentally and theoretically. The proposed model is based on the assumption of a pure diffusion of the complex salt [K·L]+SCN¯ through the liquid membrane stagnant films at the interfaces. It illustrates the ...

A kinetic study of mercury(II) transport through a membrane assisted by new transport reagent

BACKGROUND A new organodithiophosphorus derivative, namely O-(1,3-Bispiperidino-2-propyl)-4-methoxy phenyldithiophosphonate, was synthesized and then the kinetic behavior of the transport process as a function of concentration, temperature, stirring rate and solvents was investigated. RESULTS The compound 1 was characterized by elemental analysis, IR, 1H and 31P NMR spectroscopies. The transp...